It is a synthetic and specific inhibitor of activated factor x xa. Each singledose, prefilled syringe of arixtra, affixed with an automatic needle protection system, contains 2. Arixtra fondaparinux sodium dose, indications, adverse. Arixtra is indicated for the treatment of acute pulmonary embolism when administered in conjunction with warfarin sodium when initial therapy is administered in the hospital. Do not mix other medications or solutions with arixtra.
Highlights of prescribing information these highlights do not include all the information needed to use coumadin safely and effectively. Portola provides easy access information and copay support for you and your eligible patients. Bevyxxa is indicated for the prophylaxis of venous. Important reminder at the end of this policy for important regulatory and legal information. Arixtra is supplied as a sterile, preservativefree injectable solution for subcutaneous use. Added bridge to or contraindication to warfarin for dvt and pe. Spinalepidural hematomas see full prescribing information for complete boxed warning. Highlights of prescribing information these highlights do not include all the information needed to use pradaxa safely and effectively. Arixtra fondaparinux sodium solution for subcutaneous injection. Call your doctor for medical advice about side effects. The study will be conducted in several eu countries. What arixtra is and what it is used for arixtra is a medicine that helps prevent blood clots from forming in the blood vessels an antithrombotic agent. Gsk is not responsible for content on thirdparty websites. For more information about arixtra, contact mylan at 18774463679 18774inforx.
Initial day 1 dose is 160 mg, or two 80mg capsules. Highlights of prescribing information these highlights do not include all the information needed to use arixtra safely and effectively. Arixtra fondaparinux sodium injection usp qualitative. Prophylaxis of dvt following hip or knee replacement. Refer to the prescribing information for oral aripiprazole for recommendations regarding dosage adjustments due to drug interactions, for the first 21 days when the patient is taking 21 days of oral aripiprazole concomitantly with the first dose of aristada.
Each single dose, prefilled syringe of arixtra, affixed with an automatic. Arixtra contains a synthetic substance called fondaparinux sodium. Side effects of arixtra fondaparinux sodium, warnings, uses. Fondaparinux is a pentasaccharide synthetic derivative of unfractionated heparin ufh and lowmolecularweight heparin lmwh. No dosage reduction is required for patients with mild renal impairment creatinine clearance. Arixtra, innfondaparinux sodium european medicines agency. Angiomax is intended for use with aspirin 300325 mg daily and has been studied only in patients receiving concomitant aspirin. This is not a complete list of side effects and others may occur. Arixtra fondaparinux sodium solution for subcutaneous injection initial u. Fondaparinux is a synthetic anticoagulant with selective inhibition of activated factor x factor xa. If you are not the intended recipient, please notify the sender immediately. Added continuation criteria for vte in presence of cancer.
Arixtra is a medicine that helps prevent blood clots from forming in the blood vessels an. Forhycamtin for injection in combination with cisplatin, reduce the dose to 0. Highlights of prescribing information these highlights do not include all the information needed to use eliquis safely and effectively. The antithrombotic activity of fondaparinux sodium is the result of antithrombin iii atiiimediated selective inhibition of factor xa. Arixtra prescribing information version 92020, glaxosmithkline, research triangle park nc and garcia, et al. Arixtra fondaparinux sodium injection usp qualitative and quantitative composition each prefilled syringe contains 2. Take advantage of gsk product and disease state webinars to increase your medical knowledge. Highlights of prescribing information these highlights do not include all the information needed to use rebetol safely and effectively. Consider how bevyxxa may help the acutely ill medical patients you see in your practice. You are leaving gsk pro to visit a separate website not associated with gsk pro, a portal for us healthcare professionals. Arixtra fondaparinux sodium injection solution for subcutaneous injection. These instructions are for both types of syringes automatic and manual.
Arixtra fondaparinux dosing, indications, interactions. Arixtra is given to you as a subcutaneous injection an injection just under the skin. Information and interactions fondaparihux in this web site are for information purposes only and are not intended to be used to diagnose, treat, cure or prevent any disease. Full prescribing information 1 indications and usage avonex is indicated for the treatment of relapsing forms of multiple sclerosis ms, to include clinically isolated syndrome, relapsingremitting disease, and active secondary progressive disease, in adults. Each single dose, prefilled syringe of arixtra, affixed with an automatic needle protection system, contains 2. In patients undergoing surgery, the timing of the first. The primary objective is to evaluate physicians adherence to fondaparinux prescribing information for the treatment of patients with svt without concomitant dvt. These highlights do not include all the information needed to use lovenox safely and effectively. The synthetic pentasaccharide arixtra or fondaparinux is an indirect antixa that effectively inhibits thrombin generation via its binding to antithrombin, the cofactor for xa. Bleeding risk see full prescribing information for complete boxed warning. The information provided is intended for use as a general guide only.
Mylan manufactures arixtra fondaparinux sodium injection, solution arixtra in strengths of 25 mg05 ml 5 mgml5 mg04 ml 125 mgml75 mg06 ml 125 mgml10 mg08 ml 125 mgml. Arixtra fondaparinux sodium injection is a sterile solution containing fondaparinux. The recommended dose of angiomax is an intravenous iv bolus dose of. Even though every effort has been made to ensure the accuracy and completeness of the information.
The test cannot distinguish between fondaparinux unfractionated and low molecular weight heparin. Arixtra contains the active substance fondaparinux sodium 1. A wellexecuted and designed clinical development of fondaparinux in venous thrombosis prophylaxis demonstrated success of this agent and thus its fda approval. Pradaxa dabigatran etexilate mesylate capsules, for oral use. For any information about this medicinal product, please contact the local. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for arixtra fondaparinux. There are website links to thirdparty sites on gsk pro. No dosage reduction is required for patients with a creatinine clearance greater than or equal to 30 mlmin. If you received this document by mistake, please know that sharing, copying, distributing or using information in this document is against the law. Arixtra fondaparinux sodium injection usp qualitative and. Coumadin warfarin sodium tablets, for oral use initial u. American college of chest physicians accp guidelines assign low evidence rating to treatment of hit with fondaparinux and conclude that further studies evaluating its role in hit treatment are needed.
Read the patient information leaflet if available from your pharmacist before you start using fondaparinux and each time you get a refill. Arixtra fda prescribing information, side effects and uses. Lovenox enoxaparin sodium injection, for subcutaneous and intravenous use initial u. This patient information has been approved by the u.
Arixtra is a solution for injection in a prefilled syringe. It possesses increased affinity to inhibit factor xa compared with ufh and lmwhs. The injection should be kept at room temperature less than 25 degrees c. Learn about arixtras dosage, side effects and indications. Arixtra fondaparinux sodium injection, solution arixtra 25.